WOW, what a book -- a perfect guide for those just embarking on a medical journey and a valuable resource for people like me -- already surviving a major illness -- who wish to better manage their health care for all of time.

Author Laura Nathanson, MD, wrote What You Don't Know Can Kill You: A Physician's Radical Guide to Conquering the Obstacles to Excellent Medical Care in honor of the husband she lost after a series of misdiagnoses and for everyone wishing to prevent such tragedy in their own lives.

Nathanson offers readers techniques for identifying signs of misdiagnosis and misleading analysis of symptoms. She shares tips for preventing medical miscommunication, keeping safe in the hospital, and choosing health care plans without falling into the uncovered services trap.

The allure of this book is the easy, non-medical approach Nathanson uses as she urges everyone facing the medical world to take charge of an often inpenetrable system. For the patient who is no stranger to this world, Nathanson's words will ring abundantly true.

"When I look back on that long period of delayed diagnosis and how we were then and later bounced around from one medical specialist to another, the image that pops into my head is that of a slightly mad, grotesque volleyball game -- with the patient as the ball," she writes.

For the patient new to medical confusion, Nathanson's words will impart volumes of truth.

"Here's what I've learned, and what you must learn if you wish yourself and your loved ones to survive a bout with serious illness," she reports. "No matter who you are, physician or not, lucky or not; no matter how rich, famous, successful, good-looking, innocent, kindly or powerful; no matter how close and trusting the relationship you have with those providing your medical care -- you cannot rely on today's medical system to keep you healthy, safe and alive."

Amen.

The skin cancer we so desperately try to avoid may be caused, in part, by the very thing we use to prevent the disease -- sunscreen.

Scientists at the University of California report in the journal Free Radical Biology & Medicine that some of the chemicals found in sunscreen products can become cancer-causing agents once they are absorbed into the skin.
And perhaps this is why more and more people are developing skin cancer, despite the increasing use of sun lotions.

"Sunscreens may be doing more harm than good," says lead researcher Dr. Kerry Hanson.

May is the important word here. Sunscreens may contribute in some way to the incidence of skin cancer. But the jury is still out. And experts are not sure right now how significant this research will be in the long run.

Bladder cancer is diagnosed in 55,000 - 60,000 individuals annually in the United States. Patients whose cancer has spread to deeper tissues in the bladder and/or nearby lymph nodes may be treated with a radical cystectomy, the surgical removal of the bladder and nearby lymph nodes.

This approach may be able to cure the patient, however recurrences do occur. Researchers want to find out which patients may be more susceptible to a recurrence so that they can either monitor them more closely or treat them more aggressively to reduce the risk of recurrence.

An article was published in Lancet Oncology saying that markers may help predict the risk of cancer recurrences in patients who are treated with a radical cystectomy. Researchers from Texas and Canada conducted a clinical study to evaluate markers found in the the tissue samples taken after surgery. The markers tested included the expression of Bcl-2, caspase-3, P53, and survivin.

The study found that those patients that had an altered expression of Bcl-2, caspase-3, P533 and survivin were associated with over four times the risk of cancer recurrence. Also, the altered expression of all of these bio-markers was associated with nearly seven times the risk of death from cancer.

The researchers conclude that these findings support other studies that show these bio-markers can help predict who will remain cancer free. They look at this as moving forward towards more individualized treatments for the patients.

It did not say in the article whether using this test after the surgery would help them to determine if chemotherapy or radiation would be something that could reduce the risk of recurrence if the markers would show a high risk category of recurrence. I think this these studies are great but we need to be moving forward to get the patients to benefit from this vital information.

In a radical new approach to attacking cancer, researchers will soon attempt to kill tumors by infecting them with viruses that cause ailments like the common cold.

This virus therapy treatment -- considered the third pillar alongside chemotherapy and radiation -- could one day become standard battle against cancer.

One Belfast doctor says anything that could improve the lives of cancer patients is worth a try. And try is exactly what Leonard Seymour, Professor of Gene Therapy at Oxford University, plans to do when he begins leading trials later this year.

Seymour, who has been working with viruses that kill cancer cells while sparing healthy tissue, will use a stealth virus masked from the body's immune system with a polymer coat that could travel through the bloodstream and reach tumors.

Two viruses are likely candidates for study in the first clinical trials -- adenovirus, cause of a cold-like virus, and vaccinia, cause of cowpox and a component in the smallpox vaccine.

Preliminary research on mice shows that virus therapy works well on tumors resistant to standard cancer drugs. But several years of trials will be necessary before the therapy can be considered for use on all cancers.

A recent study has shown that extracapsular extension (ECE) of the lymph nodes in patients with bladder cancer is no longer a bad prognostic finding. ECE is caused when cancer cells break through the capsule of the lymph node and can spread to nearby tissues.

The study suggests that, with the new adoption of combined therapies instead of single treatment modalities, extracapsular extension is not considered a poor prognostic factor. At this time in the treatment for bladder cancer ECE does not carry as much weight as was previously believed. The researchers evaluated 108 patients with bladder cancer who underwent radical cystectomy. ECE involved lymph nodes was present in 41 percent of patients but the findings concluded that it was not significantly associated with overall survival or relapse free survival.

Since 1988, Wendy Chioji has been a reporter and anchorwoman for WESH 2 News in Orlando, Florida. She has covered news ranging from the pope's visit to Cuba in 1998 to the Olympic Winter Games in Salt Lake City in 2002. She continuously covered last year's hurricanes, and she has an Emmy award under her belt for a special news report on heroin use.

Wendy is a top notch athlete. She has run five marathons and competed in several triathlons and half-ironman races. She has ridden in parts of several stages of the Tour de France, and traveled across the country with Lance Armstrong in 2003 -- covering 550 miles -- with the Tour of Hope event to raise awareness for cancer research. Wendy has also made a tour with stage II breast cancer. Since 2001, she has been surviving this disease.

Long term survival for patients with advanced ovarian cancer can be achieved says an article published in the Journal of Surgical Oncology. The patients would need to undergo radical surgery and intraperitoneal chemotherapy.

So what does this mean? Intraperitoneal chemotherapy is when the patient gets chemotherapy delivered to the site of the cancer before being metabolized and broken down through our body's metabolic processes. Hyperthermic intraoperative chemotherapy (HIIC) is when the heating of tissues is added to aid in the uptake of chemotherapy into the tissues.

Researchers in Spain did a study that involved 19 patients who were recently diagnosed and 14 patients that had recurrent ovarian cancer. Patients underwent radical surgery and HIIC with the chemotherapy agent Taxol.

The researchers concluded that radical surgery followed by HIIC resulted in impressive survival among patients with advanced ovarian cancer.

According to a news report, last October, Grammy Award-winning opera singer Sylvia McNair had a mammogram that did not indicate the presence of breast cancer. However, within less than a year, McNair went on to be diagnosed with breast cancer, and is currently recovering from a radical mastectomy and chemotherapy.

With more chemotherapy ahead of her, and a new position as a voice instructor at Indiana University, she stated, ""My future is going to be a hybrid combination of teaching and continuing to sing concerts and productions of musical theater pieces. But obviously, my near future is going to involve winning over cancer, which will happen. If cancer has taught me one thing, it's that life is a puzzle with many pieces, and cancer is one of the pieces of life."

McNair, who performed for Pope John Paul II and has sung at the U.S. Supreme Court, won two Grammy Awards - in 1994 for Handel's Semele and in 1996 for The Echoing Air: The Music of Henry Purcell.

In 2002, Sylvia McNair acted as the evening's narrator for Sing for the Cure in a tribute to Kenda Webb, who lost her battle with cancer the year before after serving as co-honorary chairperson for the Sing for the Cure event. Accompanied by Charles Webb on piano, McNair performed a selection of American Songs from Broadway and Bernstein. Slyvia McNair is considered one of the world's greatest living sopranos.

Earlier this month, I shared the results of a study that drinking coffee reduces the risk of a genetic type of breast cancer. Good news for women who enjoy a cup of java -- or two -- or three -- to start the day. I have found more good news about coffee. Did you know that a cup of coffee is the number one source of antioxidants in the U.S. diet? So this could mean that we do not get very much in the way of antioxidants in our diet, or it might be that coffee has antioxidant super powers.

"Americans get more of their antioxidants from coffee than any other dietary source. Nothing else comes close," says study leader Joe Vinson, Ph.D., a chemistry professor at the University of Scranton.

Dr. Vinson explained that, "Although fruits and vegetables are generally promoted as good sources of antioxidants, the new finding is surprising because it represents the first time that coffee has been shown to be the primary source from which most Americans get their antioxidants." Antioxidants protect from the potential damage to cells of free radicals. Past research findings have indicated that coffee provides a certain level of cancer prevention for breast, colon and liver  cancers.

Researchers analyzed the antioxidant content of more than 100 different food items, including vegetables, fruits, nuts, spices, oils and common beverages and the amount of daily consumption. Coffee was number one on the list. According to the National Coffee Association, over 50 percent of Americans drink coffee. With all the constant news concerning what is bad for you, this is better than good news for coffee drinkers.