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Posts with tag renal

Kidney cancer makes David Foster sick

David Foster was diagnosed with Advanced Renal Cell Carcinoma in April 2005. Translation: stage four kidney cancer and the sixth deadliest form of cancer. Not a great disease to acquire. Also not the end of the world. Just ask David who is busy working as a National Strategic Advisor in Augusta, Georgia, headlining within the independent magazine community, hanging out with dog Gracie, and documenting his journey in a blog he calls David Foster's Kicking Kidney Cancer's Arse.

He's no wimp, this guy. Just read his June 23 post, titled May kill me, but it ain't gonna beat me. He didn't let that hard-nosed kid Jerry whip him when he was eight -- he smacked him so hard in the lunchroom, Jerry was left stumbling and bleeding -- and he won't let cancer bully him either. Still, David admits: he is sick. He explains it all in a post he calls Mr. Foster, are you really sick?

David got an e-mail one day. It read, Mr. Foster, are you really sick? I read your blog and you don't sound sick.

Continue reading Kidney cancer makes David Foster sick

FDA gives stamp of approval for kidney cancer drug

New cancer drug Torisol was approved on Wednesday by the FDA for use with renal cell carcinoma, an advanced form of kidney cancer.

Torisol, also known as temsirolimus, is an enzyme inhibitor made by Wyeth Pharmaceuticals and has shown promise for prolonging patient survival. It's the third kidney cancer drug approved in the past 18 months -- the other two are Nexavar, intended to delay disease progression, and Sutent, for tumor size reduction.

Many kidney cancer patients are cured by surgery. About 35 percent of patients, however, experience a recurrence or a spread of the disease. Until just recently, there were no effective drugs to control these issues. Now there are several -- and Torisol is the one showing modest improvement in survival for patients with the most advanced tumors. Further study will indicate whether or not the drug is useful for patients with less extensive metastatic disease.

Turning a negative to a positive

The beloved member of our family, Spotted Calamity Jane, the oldest of our two Dalmatians had to be put down on February 17. It was the hardest decision I personally ever had to make, knowing when it was time to put her out of too much pain. The tears continue to flow and I know will for a long time. She had survived breast cancer at the age of 4 and continued to live a happy life loving her runs on the beach. 2 1/2 years ago she was diagnosed with renal failure, something that is irreversible but we continued to give her a low protein diet and top notch vet care and monitoring that included some acupuncture. It came to a point where we knew the pain was outweighing the good quality of life and the end was not far away and it was time to end the suffering. For 13 years she brought us joy and laughter and unconditional love. She was the leader and companion to our other 8 year old Dalmatian Kiva, who is deaf and followed Cally everywhere watching everything that she did. Watching the two of them running and playing on the beach in the water and sand are memories I will always carry. So we decided to have Cally cremated so we could spread her ashes out on the beach that she loved so much.

Then we were faced with another heart break. Seventeen days later we were told that her ashes had been lost and it floored us. It sent me curled up in a bed crying for a whole day. Family members and friends were outraged as our hearts once again tried to overcome the loss. We were told to get an attorney and sue for compensation. In quietness I walked through the trails in the woods near our house and thought what good could come from all of this. The vet of course refunded our money and offered to buy a memorial stone or something for us. I told him we would think about things. Then I decided that her life and the joy that she brought us should go to something positive and that I did not want to go through the stress and negativity of a law suit and staring at a meaningless stone memorial would not make it any better. That wouldn't change anything. So I suggested to the vet and the cremation services company, to donate money to my favorite charity, Indie Music For Life, that works with independent singer songwriters and comedians to raise money for cancer research and educational awareness programs on the benefits of music and laughter as therapy to cancer patients. This turned the tragedy into a positive. We have the great memories of her life with us and the knowledge that even in her death she has brought more good to the world. Cally is the beautiful dark colored Dalmatian on the left in this picture. Her spots continued to grow and grow which made her look like a black Dalmatian with white spots. We called her "our little negative" for those of you in the photography field that understand reverse imaging. She was a rare jewel and always a positive in our lives.

Drug on the fast track for FDA approval to treat advanced kidney cancer

Torisel is a protein inhibitor to be filed for approval for the treatment of cancer. It's an investigational drug that inhibits mTOR, a protein that regulates cell proliferation, cell growth and cell survival.

Wyeth Pharmaceuticals is seeking an indication for Torisel for the treatment of advanced renal cell carcinoma. If approved this drug would be a significant improvement compared with existing therapies. Results from a Phase III clinical trial showed that out of 626 patients, overall survival was increased by 49 percent.

Torisel will be available prior to FDA approval through an Expanded Access Program (EAP). For more information you can call 1-800-234-8243 or go to the website www.clinicaltrials.gov.

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