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Posts with tag repair

Thought for the Day: Cancer, for the layperson

Cancer is a complicated disease often described by those who know it well in confusing medical, technical, and scientific terms. There's a way to understand it in simple terms, though. And a recent CBS news story features a great run-down on the disease, its causes, how it grows, and more.

Think about this:
  • Cancer refers to any one of a large number of diseases characterized by the uncontrollable growth of abnormal cells. These cells have the ability to infiltrate and destroy normal tissue and can spread -- metastasize -- throughout the body.
  • Cancer is caused by damage in the DNA. DNA is like a set of instructions for cells and tells cells how to grow and divide. Normal cells can develop mutations in their DNA but can repair most of them. If they cannot make a repair, the cells often die. But certain mutated cells don't repair and don't die. They instead grow and become cancerous.
  • Normal, healthy cells grow in an orderly, well-controlled way. They live for a set period of time and then die on schedule. Dead cells are replaced by new normal cells. Cancer cells, in contrast, grow in an uncontrolled manner. They don't die. They accumulate. One malignant cell becomes two, two become four, four become eight, and so on, until a mass of cells -- a tumor -- is created. Tumors remain small until they're able to attract their own blood supply, which allows them to obtain the oxygen and nutrients they need to grow larger.
  • Not all cancers form tumors. Leukemia, for example, is a cancer of the blood, bone marrow, lymphatic system, and spleen.

  • Cancer can take decades to develop. By the time a cancerous mass is detected, it's likely that 100 million to one billion cancer cells are present, and the original cancer may have been dividing for five years or more.
  • Lung cancer is the top cancer killer among men and women and will kill 160,390 people in 2007.

New gene discovery is small piece in breast cancer puzzle

Researchers have identified a damaged gene -- BRIP1 -- that doubles the risk of familial breast cancer in a small percentage of women. BRIP1 is a DNA repair gene that can lead to uncontrollable cell growth if not functioning properly. Researchers have concluded that the damaged gene increases risk for breast cancer from eight to 16 percent by age 70.

These findings won't change patient care but they may offer comfort to women who develop breast cancer and cannot pinpoint the occurrence to the commonly mutated BRCA1 and BRCA2 genes -- mutations that are responsible for the disease 80 percent of the time. And while the study of BRIP1 does add to the pool of research on breast cancer, it does not warrant screening at this time. It's just a small piece of the puzzle that one day may prove significant. For now, the risk of breast cancer resulting from a damaged BRIP1 gene is modest.

Baby teeth rich in stem cells, may one day save lives

Parents may want to save their kids' baby teeth for more than just nostalgic reasons -- they may want to save them because they are rich in stem cells and the pulp tissue could provide the means to treatment for injuries and disease. BioEden Inc. is a new company out of Austin, Texas pioneering this effort that is so new some doubt science will ever catch up with the expectations of this firm. But President Jeff Johnson says all evidence indicates that baby teeth are a wonderful source of stem cells -- cells that doctors and researchers pursue for their capability of replicating and morphing into specialized cells that can be used to repair the body. Experts think baby teeth stem cells might one day be used for bone, teeth, and even nerve cell regeneration which could hold potential for spinal cord injuries and Alzheimer's and Parkinson's diseases.

Parents may find brochures in their dentist offices featuring the benefits of banking their children's teeth once they fall out. And pursuing tooth banking is no different than pursuing any other dental procedure. There are fees involved, of course -- banking fees and perhaps referral fees from dental offices -- and other considerations that each parent must weigh. Dr. Phil Hunke, president of the American Academy of Pediatric Dentistry and pediatric dentist for 32 years, says the idea of removing cells and freezing them holds true promise -- and he may want to bank the tooth of a child or grandchild once he learns more. Dr. Kevin Donly, a professor of pediatric dentistry, says he sees some potential but will not be banking teeth for his three little boys. He just doesn't think he's at the point where it's necessary. Another pediatric dentist -- Dr. John Updyke -- believes that if money were not an issue, all parents should bank their kids' teeth. But many young families can't afford the initial $595 and the $89 annual storage cost it requires. And without a solid scientific backing, tooth banking might not come up as a priority for many when it may take 10 years or more to even determine how useful these specific stem cells will be.

Cancer caregiver becomes hero for wife, spreads his word

Caregivers are affected by cancer in their own unique and special ways. And those of us who have never been cancer caregivers and those of us who are patients receiving the care will never really know how it feels to walk in caregiver shoes -- until we do it ourselves.

Dr. Mitchell Luftig has done it himself. And after traveling a dark and unwanted journey of caring for his wife with breast cancer, he realized that he had learned a thing or two -- and he learned that he could share a thing or two. So he wrote a book, Be a Hero To The Woman You Love When She Gets Sick, and he speaks openly about his role as caregiver -- and his role at the time as father of twin high school daughters and husband of 20 years and clinical psychologist too. The whole ordeal turned his world upside down and he hopes that his story helps others -- primarily men -- who find themselves in a lonely place with the daunting job of caring for the people they love. As a psychologist, Luftig has good insight. And he wishes to help minimize the psychological barriers that prevent men from effectively caring for loved ones during times of serious illness.

Luftig shares in his book his realization that while he cannot repair and fix all hard times, he does have some important tools. And his power tools are love, support, and understanding. He has learned to sew joy out of rough cloth. He understands that he cannot shelter his family members from bad times, but he can shoulder their burden. And he now appreciates that all things are not so bad when measured against the yardstick of a life-threatening disease like cancer. Luftig's whole collection of wisdom and lessons and advice fill his book -- and bits and pieces also appear in periodic articles in Coping magazine. It's worth the read -- and the journey starts here.

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