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Posts with tag researchers

Thought for the Day: Sweet news from the FDA

The Food and Drug Administration (FDA) has something important to say about the sugar substitute aspartame.

Think about this:

Italian researchers concluded in 2005 that aspartame causes cancer. But Laura Tarantino of the FDA Office of Food Additive Safety concludes after a review of the study data that the low-calorie sweetener is not a carcinogen.

A similar review by the FDA's European counterpart agrees. There is no evidence this substance, used for 25 years to sweeten soda, gum, dairy products, and some medications, causes cancer.

Italian researchers say they will release their latest aspartame study results on Monday.

April is Cancer Control Month, says President Bush

President Bush, in a recent press release, declared April Cancer Control Month. It's a month for educating Americans about cancer, for raising awareness about treatments, for renewing the commitment to fighting this deadly disease.

Bush makes no mention in his release of the millions he just cut from the National Cancer Institute budget and how this might hinder this month's initiative, but he does offer a few relatively inexpensive ideas for individuals who wish to minimize their risk of developing the disease that remains the country's second leading cause of death.

"Individuals can reduce their risk of developing cancer by practicing healthy eating habits, exercising, limiting sun exposure, avoiding tobacco, knowing their family history, and getting regular screenings from the doctor," he writes.

Bush goes on to honor those lost to cancer and commends the strength of the 10 million people in the United States surviving the disease. He extends his gratitude for medical professionals, researchers, family members, and friends who support cancer patients. And he closes with a little history -- and his very own proclamation.

"In 1938, the Congress of the United States passed a joint resolution (52 Stat. 148; 36 U.S.C. 103) as amended, requesting the President to issue an annual proclamation declaring April as 'Cancer Control Month.'

NOW, THEREFORE, I, GEORGE W. BUSH, President of the United States of America, by virtue of the authority vested in me by the Constitution and laws of the United States, do hereby proclaim April 2007 as Cancer Control Month. I encourage citizens, government agencies, private businesses, nonprofit organizations, and other interested groups to join in activities that will increase awareness about the steps Americans can take to prevent and control cancer.

IN WITNESS WHEREOF, I have hereunto set my hand this twenty-ninth day of March, in the year of our Lord two thousand seven, and of the Independence of the United States of America the two hundred and thirty-first."

GEORGE W. BUSH

Low-dose birth control pills cut ovarian cancer risk

Newer versions of oral contraceptives -- with lower levels of estrogen and progestin -- reduce the risk of ovarian cancer more than older concoctions of birth control pills

Researchers at the University of Hawaii in Honolulu, whose work is published in the Journal of Obstetrics & Gynecology, say birth control pills have long decreased the risk of ovarian cancer. But over the years, doses of hormones in these pills have been decreased to reduce side effects -- and this seems to have an even stronger protective effect against the disease.

Studies show for women who had used any oral contraceptive a 50 percent reduction in risk of developing ovarian cancer compared to women who had never taken the pills. This risk was reduced by 38 percent
for women who took high estrogen and high progestin pills and by 81 percent for those taking pills with low levels of these hormones.

"Up to 42 percent of ovarian cancers might have been avoided if all women used some form of combined oral contraceptive pills," say researchers.

"An estimated 73 percent of ovarian cancers might have been avoided if all women used oral contraceptive pill formulation of low estrogen and low progestin."

Link found between arthritis and cancer

British researchers have found a connection between inflammatory polyarthritis, rheumatoid arthritis, and cancer. The connection -- a 40 percent increase in cancer mortality in patients with both arthritis conditions.

This is a striking finding, say researchers, whose study is published in the March issue of Arthritis & Rheumatism.

"The results of this study demonstrated that five-year cancer survival in patients with IP is substantially reduced in comparison with that in the general population, even after adjusting for differences in age, sex, and cancer site, whereas the overall cancer incidence does not seem to be increased," says study leader Dr. Alan Silman, an epidemiologist with the University of Manchester.

Cancer drug Avastin fights brain tumors too

Lung and colorectal cancer drug Avastin has been tested for the first time against the most common and deadly form of brain cancer.

Duke University researchers used Avastin, known chemically as bevacizumab, in combination with a standard chemotherapy agent in patients with recurrent brain tumors called gliomas. Good news -- the two drugs together stopped tumor growth for twice as long as any other therapy.

Gliomas are mostly incurable in all cases, but this new treatment approach may extend life and may help preserve physical and mental function for a longer period of time for patients fighting this deadly disease.

"These results are exciting because of the possible implications for a patient population that currently has the poorest possible prognosis going into treatment -- those with malignant brain tumors that have recurred after initial treatment," says the lead researcher whose findings appear in the journal Clinical Cancer Research.

Secondhand smoke to blame for many lung cancer cases

Nearly 20 percent of women and eight percent of men with lung cancer have never smoked, say researchers involved in a study of one million people in the United States and Sweden. The likely culprit in these lung cancer cases is secondhand smoke.

It's not yet clear why women are more likely to develop the disease. Perhaps they are more susceptible to all forms of smoking -- whether direct or secondhand -- or maybe because more men smoke than women, women are more likely to be exposed to secondhand smoke.

While smoking is the leading cause of lung cancer, there are other factors to blame for disease incidence. Radon, asbestos, chromium, and arsenic are all associated with lung cancer.

According to the American Cancer Society, lung cancer will be diagnosed in 213,000 Americans in 2007. The disease will kill 160,000.

Sunshine in the forecast for skin cancer prevention

Way back in my sun worshipping days -- when I longed for a golden tan, logged countless hours scorching my body, and ignored my grandma's warnings that my pale skin was just not tough enough for the sun's powerful rays -- I would have basked in joy over headlines now surfacing in the media. They go something like this: the sun may actually fight skin cancer instead of causing it.

According to a team of scientists at the University of New Mexico's Cancer Research and Treatment Center, a little bit of ultraviolet B light is enough to stimulate a vitamin D immune response in the skin -- but it's not enough to boost skin cancer risk.

It's still true that sunlight is the main cause of skin cancer. But limiting exposure is the key to preventing the disease -- and for promoting bone health and perhaps preventing colon cancer too.

Researchers, whose findings are published in the March issue of
Nature Immunology, suggest staying out of the sun for now -- because they don't yet know what constitutes a little bit when it comes to UVB rays.

Researchers make unexpected breast cancer discovery

Canadian researchers have made an unexpected discovery in a molecule that appears to drastically boost the ability of standard drugs to kill breast cancer cells. Currently, the discovery has been confined to the lab -- but researchers hope the power of this molecule, the ANK peptide, can one day be used to counter drug resistance for many women with breast cancer.

Scientists from Queen's University say the ANK peptide, not a drug by itself, gives drugs like taxol and nocodazole more than triple the ability to kill breast cancer cells. One scientist says the process of enhancing drug effectiveness is much like adding flavor to coffee to make it taste better.

This is exciting news, but the results -- published Monday in the journal Cancer Research -- only apply to lab experiments at this point. Researchers must now proceed with testing the peptide-drug combination in lab mice. If successful, they will move on to human testing. The whole process could take years. But early results are so promising that application for a U.S. patent on the peptide has already been made.

According the medical experts, breast cancer patients can become resistant to some drugs depending on duration of treatment, dose of medication, and genetic makeup.

"This peptide would be able to give them another chance," said a researcher from this study. "For those who respond reasonably well, they will do even better; for those who don't respond to this drug treatment ... we greatly hope this will make the current drug more useful by extending its impact to a wider range of people, particularly those with a resistance problem."

Power of prayer a factor in cancer survival

Evangelical preacher Darlene Bishop believes prayer can cure cancer. She wrote a book about it, and she convinced her brother to abandon conventional cancer treatment so he could fully pursue the power of prayer. Sadly, his pursuits were unsuccessful and he died 18 months ago from throat cancer. Now Bishop is in the midst of a multi-faceted legal battle with family members who claim she did her brother wrong. Maybe she did.

Perhaps prayer alone can't cure cancer, but a new study does indicate prayer can be of great benefit to some people following a cancer diagnosis.

Researchers at the University of Wisconsin looked at transcripts from 97 breast cancer patients active in an on-line support group. They found patients who wrote more religious words -- like prayer, worship, faith, and holy -- had less negative emotions than other patients. They also had higher levels of overall well-being.

This study, also revealing prayer has the same effect regardless of specific religious practices, lends support to research showing cancer patients with positive purpose in their lives fare better through their journeys than those floundering in negativity.

Fruit, veggies, milk lower liver cancer risk

You're in luck if you like fruit, vegetables, and milk -- because Italian researchers say these items appear to reduce the likelihood of developing liver cancer.

Diet plays a significant role in the risk of liver cancer, says the lead researcher of this study who singles out fruits and vegetables as the foods with the most protective effect.

Subjects of this study -- published in the International Journal of Cancer -- were 185 patients with liver cancer and a comparison group of 412 controls without cancer. Participants responded to questions about diet, and their answers showed that as intake of certain foods went up, the risk of liver cancer went down. Factoring out other issues possibly contributing to this indication, researchers found that high intake of milk and yogurt cut the risk of developing liver cancer by 78 percent. High consumption of white meat lowered the risk by 56 percent, and when combined with high intake of fruit, this number dropped to 52 percent.

These finding are particularly important for patients with hepatitis B and hepatitis C (HCV) infection. But overall, experts say anyone wishing to ward off liver cancer should adopt a diet rich in fruits and vegetables, limit alcohol consumption, and avoid HCV infection by practicing safe sex and never sharing needles.

Timing of weight gain influences breast cancer risk

Carrying extra weight is a risk factor for developing breast cancer. But it's not been clear how the timing of weight gain affects this risk. Evidence is mounting, though, and it's now believed that weight gain in adult life is more predictive of breast cancer risk than absolute body weight.

A new study, published in December's International Journal of Cancer, reveals a link between gaining weight in adulthood and an increased risk of breast cancer after menopause.

"We did find some suggestion that weight gain during the 30s and 40s, weight gain since a woman's first pregnancy and weight gain since menopause, especially for women with a longer time since menopause, may all be of importance in relation to postmenopausal breast cancer risk," report the researchers who followed 1,166 women with breast cancer and 2,105 without the disease.

A 70 percent increased risk was found among postmenopausal women who gained more than 60 pounds between age 20 and the onset of menopause. This was in comparison to women who gained less than 20 pounds during the same period of time. Overall, there was a four percent increase in breast cancer risk for each 11-pound increase in adult weight.

Shedding pounds reduces risk of prostate cancer

Eleven is the magic number.

Eleven pounds of lost weight can reduce the risk of an advanced form of prostate cancer, according to researchers from the American Cancer Society and the Duke University Prostate Center.

Researchers, who tracked the weight of 70,000 men between 1982 and 1992 and then followed them until 2003, found men who lost more than 11 pounds had a lower risk of developing prostate cancer than men whose weight remained the same.

Studies have long shown obese men are at greater risk for prostate cancer. But this study, published in this month's Cancer Epidemiology, Biomarkers & Prevention, is the first to indicate that recent weight loss can decrease risk by roughly 40 percent.

Kidney transplant triples risk of cancer

Kidney transplants can save lives. They can also increase the risk of developing a variety of cancers, according to Australian researchers who report a risk 300 percent higher than in the general population.

Most cancers developed in kidney transplant patients have a known or suspected viral origin, suggesting the weakened immune systems in these patients limit protection against cancer.

"The immunosuppressive drugs transplant patients take lower their ability to fight off infections that can trigger malignancy", the lead researcher said. "We believe the increased incidence of infection leads to the infection that results in cancer." She also notes there is probably an even greater risk of cancer among heart and lung transplant patients because these patients receive more powerful immunosuppressive drugs.

Researchers gathered their findings by comparing the incidence of cancer in 29,000 patients with end-stage kidney disease who received kidney transplants. Data was collected beginning five years prior to transplantation, during dialysis, and after transplantation. Researchers then consulted an Australian registry to identify cancers occurring between the years of 1982-2003. They compared the statistics with the number of cancers seen among transplant patients.

These cancers included melanoma, Kaposi's sarcoma, non-Hodgkin's lymphoma, Hodgkin's disease, leukemia and cancers of the lip, tongue, mouth, salivary gland, esophagus, stomach, colon, anus, liver, gallbladder, lung, connective and other soft tissue, vulva, cervix, penis, eye and thyroid. There was also an increase in nasal cavity and vaginal cancers.

This study has important implications for future immosuppression. Patients should give considerable thought to quality-of-life transplants -- such as face transplants and hand transplants -- and should carefully weigh the risks of weakened immunity. On a brighter note, this study might help prompt research on medication that can selectively target the part of the body responsible for rejecting a transplant. Because right now, medications affect the entire immune system -- and this is what makes patients more prone to developing cancer.

Is the medical industry hiding the fact that they have a cure for cancer?

I have heard people say to me that they think there is currently a cure for cancer but the pharmaceutical companies do not want us to know about it because they make so much money treating cancer.

I think this is absolutely not true. If you think about it, everyone knows someone with cancer. I think the researchers, doctors, and those in the pharmaceutical industry would want a cure to be known to help their own families and those they know fighting the disease. It only makes sense.

The most important thing to remember is that cancer is not one single disease, but many diseases. It is possible to find a cure for one cancer but be no where near a cure for another.

Pharmaceutical companies do like to make money, so does every other business out there in the world. I like the fact that they are competing with one another. This makes it a challege for them to be the first one with the breakthroughs. Hopefully we will soon find THE breakthrough but until then I'm confident that there isn't a secret cure out there!

Cells phones don't cause cancer

Cell phones don't cause cancer, according to a major study from Denmark that tracked 420,000 Danish cell phone users -- many of them users for more than 10 years and some for more than 20 years.

In the largest ever study to yield good news about the safety of cell phones, scientists matched phone records to the Danish Cancer Registry -- a listing that records every citizen who gets the disease -- and on Tuesday, the study results were revealed.

Cell-phone users are no more likely than anyone else to develop cancer.

But the lead researcher of this massive investigation says doubts will surely linger. There is really no biological basis for concern about radio waves, he says. But people still worry.

Cell phones beam radiofrequency energy that can penetrate the outer edge of the brain, causing suspicion about the origin of various cancers. Most research has found no link between cell phones and cancer, but the phones have never been given a definite clean bill of health either.

"As the body of evidence accumulates, people can become reassured that these devices are safe," says one cell phone researcher.

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