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Posts with tag sample

A study in mouthwash

A lab in Oklahoma is studying genes for combinations that predict breast cancer risk. A look into the 100 genes gathered from each woman -- via mouthwash -- allows researchers to categorize women with standard, moderate, or high risks of developing the disease.

The study begins with a lengthy questionnaire about medical history and leads to the collection of a DNA sample. Women simply rinse their mouths with a standard mouthwash and wait for results.

Geneticist Dr. Kara Casas says she hopes that regardless of results, women will choose a healthy lifestyle with a diet low in fat and alcohol consumption and with lots of exercise too. But those in the moderate and high-risk groupings will be advised to make other lifestyle changes to help decrease their chances of getting breast cancer. They may be asked to regulate estrogen levels, for example, and to report regularly for mammograms at an earlier age.

Casas says all women have some risk of developing breast cancer. But knowing what these risks are can help them better protect themselves -- which makes tests like this so important.

A total of 12,000 samples will collected for an FDA trial. For more information about this study in mouthwash, call 903-510-1173.

FDA gives go ahead for breast cancer prediction test

Women with early stage breast cancer now have a new tool at their disposal. The tool -- called MammaPrint -- is newly approved by the FDA and while it is not yet a perfect measure, it can be used along with other information to estimate whether breast cancer is likely to return in five or 10 years.

The value of this test, that measures through computer analysis the activity of 70 genes using a sample of tissue removed from a breast tumor, is that doctors and patients can better determine course of treatments.

MammoPrint offers two results -- high risk and low risk -- and accurately picked in studies which women were at low risk at least 90 percent of the time. However, for women who were told they were at high risk for recurrence as a result of the test, just 23 percent experienced a relapse.

"You can't go all the way to the bank with this test," says FDA official Dr. Steven Gutman who argues the test is still better than having no information at all.

Agendia, the Dutch maker of MammoPrint, is exploring ways to make this one-of-a-kind product available in the United States. It has been used in the Netherlands since 2005.

"This test has enormous implications for the short-term future of cancer research in general, and is one of the truly great breakthroughs of our time," says Cancer Blog reader Gregory Pawelski with whom I am grateful for sharing this story tip with me.

Awareness of breast cancer risk is a must, every month

There are various risk factors that can contribute to the development of breast cancer. Being female is the single biggest risk factor that on its own puts all women in jeopardy. But there are other risks -- many beyond our control and some more significant than others -- that can help explain why some women are diagnosed with the most common cancer in women in the United States. And why others are not.

Continue reading Awareness of breast cancer risk is a must, every month

Sunday Seven: Seven survivor spotlight similarities

It's day 15 in this Breast Cancer Awareness Month and the survivors spotlighted on this site are stacking up. Yet we've only just scratched the surface of breast cancer survivor stories. And by the end of October, we will have only featured a very small sample of survivors everywhere. There are countless others with their own powerful stories. It's sad there are so many stories shaped by breast cancer. It's empowering too -- because breast cancer survivors are a passionate bunch. They are passionate in their fights, passionate in their beliefs, passionate in their willingness to help others.

A passionate bunch of survivors can be found here on The Cancer Blog. They are all women, of various ages, with various backgrounds, defined by different experiences. They are also quite the same -- for they have all been touched by breast cancer. And their words of wisdom are strikingly similar, despite the contrast in characteristics that define these women and their very individual battles with breast cancer.

Here are seven survivor similarities worth spotlighting.

Continue reading Sunday Seven: Seven survivor spotlight similarities

Sunday Seven: Seven survivors represent so many more

I never thought the time would come when I could fill a page with names of people I know who have cancer or have died from cancer. When my mom's very best friend died years and years ago of pancreatic cancer, it seemed a remote chance that something like that would happen to someone I know. And then slowly, either because cancer cases increased or because my awareness increased -- or both -- my list of people with cancer grew and grew and grew. And now it's quite long. And it's quite disturbing. And it's empowering too -- because most people on my growing list are surviving. And here are seven survivors who are somehow connected to me -- seven survivors who make up just the tip of the cancer iceberg in my life that stretches far and wide.

Continue reading Sunday Seven: Seven survivors represent so many more

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