There are four pages in the March 2007 Reader's Digest featuring amazing discoveries, devices, tests, and cures. And many of the snippets of information are -- yes -- somehow linked to cancer.

Think about this:

• A new ultrasound technique lets radiologists distinguish between malignant and benign breast lesions. Using elasticity imaging, researchers accurately identified harmless and cancerous lesions in almost all of the 80 cases studied. If results can be reproduced in a large trial, this technique could significantly reduce the number of breast biopsies required.

• Scientists seeking new treatment for diseases can use an online tool developed by researchers at MIT and Harvard. The Connectivity Map matches diseases with compatible drugs, based on the genetic profiles of both. So far, about 160 drugs and compounds are cataloged, and a few new uses for existing drugs have already been suggested. Eventually, all FDA-approved drugs will be included.

• For those who sometimes forget to take their pills, a new device -- that can be preloaded with up to 100 doses of medication -- could one day be implanted in the body and programmed to administer drugs via wireless signals. This device, successful in tests using dogs, was designed to deliver medicines that are less effective when taken orally.

Sometimes it seems cancer's grip is tightening. Other times, in the war against this pesky disease, it seems we are on the verge of something really great.

For chronic pain sufferers, this might be the earliest beginning of the ultimate end for unrelenting pain. Columbia University researchers have been studying how pain works at the molecular and cellular level and discovered a key enzyme that cause nerve cells to send pain messages through the central nervous system even when there is no physical pain being experienced. So although you might not actually be in physical pain any longer, if your brain is being told there is still pain, you will experience the reality of pain.

Because of this find, researchers are hoping a drug can be developed that will shut down the messengers and the message.

Researcher Richard Ambron is quoted as saying that pain is not necessary. I could not agree more and have been an advocate for quality of life issues for long-term cancer survivors who must endure chronic pain without effective relief.

Just like Ambron, I do not think it is necessary that people put up with or suffer silently in pain either, and because the current methods of treatment can lead to additional health problems, this type of research is most welcome -- and long past due.