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Posts with tag significant

Still unknown but not so significant

The doctor who read my mammogram and ultrasound results today is the same doctor who detected in my recent MRI something of unknown significance. Today, the unknown remains. But the significance is not so significant.

This doctor saw an unusual pattern of tissue in my right breast when she viewed my Friday MRI results, some sort of enhancement she didn't see in the left breast or on the MRI I had a year ago. But today's mammogram looked good and today's ultrasound did too. So I guess if three different imaging tests don't turn up anything truly suspicious and there doesn't appear to be anything to biopsy, then all is well. For now.

All that must be determined now is when I will report back for more screening to chart the state of the dense breast tissue that keeps me on my toes.

Another bullet dodged. Another day in the life of a worried breast cancer girl.

Researchers search for root of pancreatic cancer stem cells

Researchers have made a stem cell discovery that may help treat pancreatic cancer -- one of the deadliest forms of the disease.

University of Michigan scientists have found cancer stem cells in pancreatic tumors that appear to drive cell tumor growth and could lead to the development of drugs to target and kill these cells.

Pancreatic cancer kills 97 percent of people diagnosed with the disease within five years. Half of all diagnosed patients die within six months of diagnosis, and this cancer -- that spreads quickly and is rarely detected at an early state -- kills 33,000 each year in the United States alone. So any improvement in the study of this disease is a true gift.

"The clinical implications of this work are significant," said Dr. Diane Simeone, director of the Gastrointestinal Oncology Program at the University of Michigan Comprehensive Cancer Centre and lead author of the study, published in the journal Cancer Research.

"We've made baby steps in improving the survival in these patients -- on the order of a few months (longer to live) -- over the past decade or so. But we really haven't had a major breakthrough in coming up with something that has the potential to provide a cure," she said.

Simeone says killing these cancer stem cells is like pulling out the root of a weed. And she says the best way to pull out the root is to target these stem cells instead of the traditional approach of shrinking tumors by killing as many cells as possible -- an approach that may be flawed because cancer stem cells tend to resist standard therapies.

Surviving cancer is harder in New Jersey

The state of New Jersey outpaces the nation in survival of ovarian cancer -- but it lags behind when it comes to surviving endometrial, cervical, skin, mouth, and brain cancers.

New Jerseyans are still surviving cancer. But a report issued Tuesday reveals the state survival rate -- for some reason -- trails the national rate.

The difference between the state and national rates is not large -- about three percentage points separate the two -- but the racial disparity appears more significant. Survival rates for white men and women are about 10 percentage points higher than those for black men and women. This is similar to the national racial gap.

It's likely racial differences are due to later detection, later diagnosis, and less access to treatment and support services.

New Jersey survival rates also vary greatly by type of cancer, sex, and age.

Awareness of breast cancer risk is a must, every month

There are various risk factors that can contribute to the development of breast cancer. Being female is the single biggest risk factor that on its own puts all women in jeopardy. But there are other risks -- many beyond our control and some more significant than others -- that can help explain why some women are diagnosed with the most common cancer in women in the United States. And why others are not.

Continue reading Awareness of breast cancer risk is a must, every month

New gene discovery is small piece in breast cancer puzzle

Researchers have identified a damaged gene -- BRIP1 -- that doubles the risk of familial breast cancer in a small percentage of women. BRIP1 is a DNA repair gene that can lead to uncontrollable cell growth if not functioning properly. Researchers have concluded that the damaged gene increases risk for breast cancer from eight to 16 percent by age 70.

These findings won't change patient care but they may offer comfort to women who develop breast cancer and cannot pinpoint the occurrence to the commonly mutated BRCA1 and BRCA2 genes -- mutations that are responsible for the disease 80 percent of the time. And while the study of BRIP1 does add to the pool of research on breast cancer, it does not warrant screening at this time. It's just a small piece of the puzzle that one day may prove significant. For now, the risk of breast cancer resulting from a damaged BRIP1 gene is modest.

Known for her celebrity, known for cancer fundraising

Most of us know her as Elyse Keaton on the long-time ago sitcom Family Ties. Many also know her from the variety of characters she has portrayed on television specials and movies. And Meredith Baxter is also known for her support of breast cancer research -- something not so apparent or obvious but just as significant in the scope of her life in the spotlight. Like many issues she speaks out on -- women's rights, gun control, state legislative matters -- breast cancer is an issue about which she is passionate. She has appeared at Making Strides Against Breast Cancer walks and presented gifts to the cause of breast cancer research and has starred in the 1994 television movie My Breast -- about a woman who successfully battles breast cancer. And she also has her own Meredith Baxter Foundation for Breast Cancer Research which began when she donated $10,000 to the University of Minnesota Cancer Center where her foundation was started. Much of the funding for this foundation comes from Baxter herself via the profits she makes from her own skin care products that are available in gift stores around the country. She says that life has been so kind to her that she was looking for a way to share her good fortune. So she took her concern about breast cancer prevention into the business arena. And just as she soared to success as one of the best-known TV moms, Meredith Baxter is soaring to new heights -- where she hopes to help prevent and one day cure breast cancer.

Impact of cervical cancer on men

Cervical cancer awareness is on the rise, though almost no information on its effect on male partners is available. For the first time attention is being given to the impact of this disease on women's relationships and the men they love.

A five-year study on the psychological and emotional effects of the disease is being planned at the University of Surrey in the UK. The researchers will observe whether the disease bonds couples stronger or breaks them apart, as well as the effect it has on their sex lives. Described as a lonely disease by lead researcher and cervical cancer patient Alison Nightingale, its effects can be very stressful and confusing for both partners. "One small-scale study found that partners suffered the same levels of cancer-related distress as the women going through treatment," she says.

Any newly-diagnosed cervical cancer patients and their partners are encouraged to participate in the study by contacting the university.

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