Cancer is a scary word -- pancreatic cancer is beyond scary. It has one of the highest mortality rates of all cancers. Symptoms of the disease usually are hard to recognize and most patients are diagnosed in the advanced stages.

Anytime I read about a new drug that can increase the survival of this deadly disease I get excited. An early online publication of the Journal of Clinical Oncology states that the addition to the targeted agent Tarceva (erlotinib) to Gemzar (gemcitabine) can improve survival in patients diagnosed with advanced pancreatic cancer.

The Phase III clinical trial included 569 patients who were either treated with Tarceva plus Gemzar or Gemzar plus placebo. At one year the survival of those treated with the drug combination reached 23 percent. Gemzar alone had a 17 percent survival rate at one year. The study also said that more patients treated with the combination of Tarceva/Gemzar achieved stabilization of their disease.

I am hoping that sooner, rather than later this disease will not be beyond scary and will be something that can be treated, controlled and one day cured.

We cannot be silent is one slogan printed on specialty clothing offered by a company called Privacy. Other slogans include United We Cure and Mission. Purpose. Cure.

The slogans say a lot -- but the accomplishments of Carolyn Jones, Founder and President/CEO of Privacy, say a whole lot more.

Think about this:

Jones lost her mother to breast cancer on November 16, 2000 during a time when too many questions about the disease were left unanswered and not enough options were available for women fighting for their lives.

Times have changed, in part due to outspoken pioneers like Jones, who are spreading the word and funding the cause.

Part of the Privacy corporate goal is to support medical research and to educate women about early detection and treatment.

"It is very clear that more information and research is needed due to the yearly increase in new cases nationally," says Jones who cites statistics such as this: every 12 minutes a woman in America will die from complications associated with breast cancer. And this: more than 1,500 new cases of male breast cancer will be diagnosed this year.

Privacy, a California-based company with a social conscious, offers for both women and men an assortment of t-shirts, sweatshirts, jeans, hats, recommended books, accessories, breast cancer facts, and even a contest or two. A portion of all profits are donated to breast cancer initiatives with an emphasis on low-income and uninsured populations.

Check it all out right here.

Advocacy runs far and wide. Thank goodness for that.

Think about this:

A new breast cancer non-profit organization has been launched especially for South Africans affected by the disease.

Founded by Samantha Galliet, the 31-year-old breast cancer survivor who made headlines with her "David and Goliath" battle to get life-saving Herceptin treatment, created PinkLink to give patients affected by breast cancer a voice.

PinkLink, focusing on the need for self-examination and awareness to encourage prevention and early detection of this silent epidemic, is intended to be a one-stop-shop with valuable South African based information on doctors, treatments, financial considerations, and health issues.

Journey to the End of the Earth: 26th annual Dawn of a Dream benefit concert to support Children's Cancer Research Fund will be held on Saturday, November 4, 2006. In 1980 after losing their daughter to leukemia, Diana and Norm Hageboeck and their friends organized the first Dawn of a Dream benefit concert, raising $50,000. Today, Dawn of a Dream is one of the largest gala events in the Twin Cities. This year's event, held at Historic Milwaukee Road Depot, Minneapolis, will feature a few surprises along with the traditional silent and live auctions, dinner and live entertainment by Los Lobos.

Children's Cancer Research Fund is a leading non profit organization committed to funding innovative and progressive research in the fight against childhood cancer.

Late last March fans of rock legend and Aerosmith lead singer Steven Tyler became concerned over speculation that Tyler had been diagnosed with throat cancer. Even though the remaining Rockin' The Joint show dates were cancelled, everyone connected to Tyler assured the public the rumors were false. Steven Tyler did not have cancer. He was suffering from strained vocal cords and needed a rest.

At the time, bassist Tom Hamilton explained the cancelled shows by saying, "You know Steven. Anything worth doing, to him, is worth overdoing," in reference to the fact that the band had been touring more now than it did 10 years ago.

Unfortunately, several months later it was announced that Hamilton had been diagnosed with cancer.

While the rumors had quieted concerning Tyler's health, now and then something new would come to our attention that made us wonder if he was okay. A reader wrote in that he had seen Tyler at the oncology clinic at a hospital he was visiting. We kept that under our hat.

Last night, Tyler appeared on Access Hollywood and for the first time, publicly discussed his health. No, he was not diagnosed with throat cancer -- but he had faced a serious health crisis and decided to speak about it. Tyler said he had been fighting a secret battle with a silent killer -- Hep C. Diagnosed three years ago, he was told by his doctor, Deepak Chopra's brother, that it was time he sought treatment. Tyler agreed to undergo a year of chemotherapy with interferon. He stated it nearly killed him but managed to stay with it and complete treatment. Tyler had Hep C for many years, and was asymptomatic, which is typical.

During the interview, Tyler said, "Hepatitis C is the one that, of all the people in this room, at least three have it and don't know it." He would like to raise awareness about Hep C and mentioned he might appear on Oprah for that purpose. "It's one of those things people don't speak about it, but it is treatable."

Almost 4 million Americans, or 1.8 percent of the U.S. population, have been infected with hepatitis C virus (HCV); it is the most prevalent cause of chronic liver disease in the United States. 80 percent of those with Hep C have no symptoms. Chronic hepatitis C can cause cirrhosis, liver failure, and liver cancer.

If you missed the television Access Hollywood interview with Steven Tyler, the video segment of the program is available online here.

Did you know almost 4 million Americans, or 1.8 percent of the U.S. population, have been infected with hepatitis C virus (HCV); it is the most prevalent cause of chronic liver disease in the United States; and a segment of those suffering from chronic HCV, or Hep C, will develop liver cancer. Until this morning, I did not know.

But when someone close to you is diagnosed with this disease, numbers do not matter. Even if there were only two people on the planet with this diagnosis and one of the two happens to be someone you love, then it suddenly seems to become the number one disease.

In my preliminary research, I have found that 80 percent of those with Hep C have no symptoms. If symptoms do occur, they are likely to be jaundice; fatigue; dark urine; abdominal pain; loss of appetite and nausea. Skin rashes, extreme itching, muscle wasting and weight loss can also be signs of Hep C. For decades, you can have Hep C and not know it is taking its toll on the liver.

According to the National Digestive Diseases Information Clearinghouse (NDDIC), a distinct and major characteristic of hepatitis C is its tendency to cause chronic liver disease. At least 75 percent of patients with acute hepatitis C ultimately develop chronic infection, and most of these patients have accompanying chronic liver disease. Chronic hepatitis C can cause cirrhosis, liver failure, and liver cancer.

Those at highest risk for Hep C are intravenous drug users; recipients of clotting factors made before 1987; hemodialysis patients; recipients of blood and/or solid organs before 1992; healthcare workers, and infants born to infected mothers.

The treatments are harsh and can come with severe side effects that cause some to discontinue treatment. New research indicates that smoking marijuana seems to offset some of the adverse side effects of treatment and help those fighting this disease remain on treatment. Hepatitis Central has published an explanation of how Hep C infection can lead to liver cancer with Duke Researchers Show How Hepatitis Infection Leads To Liver Cancer, that I found helpful in understanding the progression of the disease.

As I say, I have just started my research this morning. With a critical eye, I will continue researching until I have exhausted every avenue of information, both conventional and alternative, that I can find. If any of our readers can suggest any resources for Hep C and/ or liver cancer, please leave this information in the comment area.

During Hearst Magazines 30 Days of Fashion and New York Fashion Week, thirty fashion photographs showcased in the photography exhibit titled Getting Ready: The Art of Choice will be auctioned by Jamie Niven of Sotheby's to benefit the Ovarian Cancer Research Fund (OCRF) whose mission is devoted to research, raising awareness and finding an ovarian cancer cure.

In 1994, Sol Schreiber founded OCRF to honor the memory of his wife, Ann, who fought for five years against ovarian cancer. The late editor-in-chief of Harper's Bazaar Liz Tilberis is credited for her influence in gaining attention for OCRF due to her numerous contacts in the worlds of fashion, beauty, and entertainment.

The photographs that will be auctioned feature works by well-known photographers Bryan Adams, Tina Barney, Patrick Demarchelier, Jessica Todd-Harper, Karl Lagerfeld, Peter Lindbergh, Matthew Pillsbury, Timothy Greenfield-Sanders, Vee Speers, and Timothy White.

In 1999, Art beCAUSE, a non-profit organization was founded by two best friends, breast cancer survivor Eleanor F. Anbinder and art gallery owner Joyce Crieger. Anbinder had been diagnosed with breast cancer and over the years of her cancer survivorship she had watched other women die from the disease.

When Anbinder was diagnosed, she did not have a family history of breast cancer. In becoming active with Massachusetts Breast Cancer Coalition, she began to wonder what was causing the increased rates of breast cancer diagnosis.

With her best friend, Joyce Creiger owner of Creiger Dane Gallery on Newbury Street, the two decided to use a percentage of the profits from art sold in the gallery to fund research to look into the environmental causes of breast cancer. Art beCAUSE supports three organizations: The National Breast Cancer Coalition, Silent Spring and Seed the Scientist. You can visit Art beCAUSE on the web to learn more about the organization's events and activities.

When we posted TV news story internet video on IBC gets 10 million hits, I did not realize how little information we have provided here at The Cancer Blog regarding this relatively rare and very aggressive form of breast cancer that accounts for one to four percent of breast cancer diagnosis. To raise awareness for a type of breast cancer most women are not familiar with, I have put together basic facts about IBC as well as IBC support and resources.

Symptoms of IBC can be:

• A warm swollen breast that does not change through the menstrual cycle or respond to antibiotics.
• Skin which is red or appears dimpled like an orange.
• Itching or pain in the breast.
• A nipple which is flattened or inverted, possibly with a discharge.
• Swollen lymph nodes under the arm or above the collarbone.
  

Some of the IBC online foundations and support groups are as follows:

Sydney Garvan Institute cancer researchers have come up with an explanation of how the growth of cancer cells resist being influenced and controlled by normal cell growth and death processes. The researchers have developed a new method that enabled them to scan the 30,000 plus genes comprising the entire genome in cancer tissue samples, which allowed widespread changes to be identified in specific parts of the genome. According to the explanation provided by the researchers, the cells deregulation has traditionally been linked to DNA mutations of single genes or deletion of large sections of the chromosome. However, they have discovered that gene silencing in cancer can also occur, in the absence of changes to the DNA sequence -- a phenomenon known as epigenetics. The team hopes that new cancer therapies, which can reverse this process, will restore the cell's normal regulation in the treatment and prevention of cancer.