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Posts with tag substance

Thought for the Day: A vaccine for breast cancer too

There's a new vaccine out there that stimulates the immune system to find and destroy breast cancer cells. In early experiments, the vaccine held off or stopped the growth of tumors in all of the mice studied. Some mice were even cured.

Think about this:

Research presented at the annual meeting of the American Association for Cancer Research reveals this vaccine is different from most under development that help kick-start the immune systems of sick patients. In this case, the vaccine tells the immune system to recognize breast cancer cells and to attack and kill them on the spot.

One researcher says breast cancer cells usually fly under the radar of the immune system. To combat this problem, the injectable vaccine uses a bacteria-type substance that is altered to contain the gene HER2/neu and also antibodies that rev up the immune system. This makes the body react and wipe out cells containing HER2/neu.

If continued studies prove promising, the vaccine would work for the 15 to 25 percent of women whose breast cancers overexpress HER2/neu.

Marijuana halts lung cancer growth by half

More and more media reports are mentioning the potential merits of marijuana. The most recent headlines say the active ingredient in the drug cuts tumor growth in common lung cancers in half and greatly reduces the ability of the cancer to spread.

Researchers at Harvard University tested marijuana's main ingredient, delta-tetrahydrocannabinol or THC, in both lab and mouse studies and say their experiments are the first to show THC inhibits the growth of cancer.

Researchers are not certain why THC inhibits tumor growth, but it could be that the substance activates molecules that arrest the cell cycle. THC may also interfere with angiogenesis and vascularization, which promotes cancer growth.

There is a long way to go in the study of THC. Yet "the beauty of this study is that we are showing that a substance of abuse, if used prudently, may offer a new road to therapy against lung cancer," says Anju Preet, Ph.D., a researcher in the Division of Experimental Medicine.

Single drop of blood determines risk for stomach cancer

Stomach cancer is hard to detect. It has no symptoms in its early stages, and there is no effective screening to detect its presence. So early detection and early treatment for this disease -- that attacks 800,000 people worldwide -- are hard to come by. In Taiwan, stomach cancer is the fifth most common cancer and the focus of study for researchers working to devise a method for detecting stomach cancer in its infancy.

A team of researchers at National Taiwan University Hospital have discovered a toxic factor -- GroES -- that causes stomach cancer. And they have discovered that a simple blood test will show either a positive or negative result for this substance, leading to immediate endoscopic exams for patients who may be at risk for stomach cancer. The test to identify GroES has already achieved a 65 percent accuracy rate.

Apparently, if the human body is infected with GroES, it produces antibodies to the factor and can cause chronic inflammation of the stomach, causing cells to rupture and proliferate. Long-term inflammation can cause stomach cancer. Researchers say about 45 percent of adults in Taiwan are infected with GroES -- and one percent will go on to develop stomach cancer.

Right now, patent applications are underway in the United States, Japan, and Taiwan. Once a kit is developed, a single drop of blood will be all it takes to determine the risk for stomach cancer.

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