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Posts with tag took

Protein nestin predicts aggressive breast cancer

Researchers from Dartmouth Medical School say they have a new way of identifying a deadly form of breast cancer that plagues 17 to 37 percent of all breast cancer patients and mostly premenopausal black women.

Identification comes in the form of locating the marker nestin -- a long filamentous protein indicating the presence of basal epithelial tumors -- which makes this type of cancer hard to diagnose and hard to treat. It also puts patients at high risk for recurrence, marked by a very short time between treatment and relapse.

"Ideally, a marker like nestin would enable clinicians to monitor these patients through frequent tests of a biomarker and, in doing so, detect the cancer before it has a chance to come back," says one professor.

Researchers must now find an effective means of detecting nestin in a clinical screening setting. It won't be as simple as a blood test -- but a non-invasive collection of mammary duct samples may enable the development of a screening tool for at-risk patients.

The Hunger Scale: Avoid eating mindlessly

Take it from Bob Greene, the supercoach who helped Oprah get into the best shape of her life, when he says we all can acquire great health and great fitness -- without calorie counting and deprivation and hardship. He details it all in his new book The Best Life Diet, and he shares a series of how-to guides in the January 2007 issue of Oprah Magazine.

One tool Greene offers as we take on the new year is a hunger scale -- to help us avoid eating mindlessly, to encourage us to get in touch with our hunger, to train us away from always watching calories.

The scale goes like this:

10: Stuffed. Approaching nausea.
9: Very uncomfortably full. Need to loosen clothing.
8: Uncomfortably full. Bloated.
7: Full. A bit uncomfortable.
6: Perfectly comfortable and satisfied.
5: Comfortable. More or less satisfied but could eat more.
4: Slightly uncomfortable. Beginning to feel signs of hunger.
3: Uncomfortably hungry. Stomach is rumbling.
2: Very uncomfortable, irritable, and unable to concentrate.
1: Weak and light-headed. Stomach acid is churning.

Greene says we should eat only when we find ourselves feeling 1, 2, 3, or 4. He instructs us to put our forks down at 5 and 6 and wait for our next scheduled meal. For those trying to lose weight, he says stop eating at 5. This is the point at which you're eating less than your body is burning.

Cancer a Hawaii top killer

Cancer is the top killer of Hawaii residents, according to the state Department of Health. Heart disease -- once the leading cause of death in this state -- is now a close second.

Cancer and heart disease together killed half of the 8,988 residents who died last year in Hawaii. While heart disease took the lives of 1,258 males and 996 females, cancer claimed 1,177 males and 959 females. Cancer is the leading killer of Hawaii residents ages 45 to 84. Lung cancer is by far the most lethal form of cancer in Hawaii.

Car crashes -- 11th on the list of leading causes of death -- dominate headlines in Hawaii when it comes to fatalities. But cancer, sadly, is to blame for taking the most lives.

Witnessing death both heart breaking, soul strengthening

I was present for death only one time in my 36 years of life. I consider this both a bad and a good thing. It's bad because I did not want my grandmother to die -- and watching it happen made it so real, so vivid, so painful. I don't think I would have ever chosen to watch my grandma die -- to watch her slip from consciousness to coma, to observe her altered body once death arrived, to witness the movement of her body on a stretcher as it was wheeled out of the house from the bedroom I still see every time I visit my mom's house. But I think I am lucky really -- and this is the good part -- because I got to be with her during her final moments. I got to watch her body as it lay still, peaceful and calm and still breathing. I got to talk to her and although she could not respond, I believe she could hear my words. And it makes me happy to know my grandma may have known I was with just prior to her flight to heaven. And after her flight, I got to touch her cool hands. I got to feel the power of the passing of one life -- a long life -- and I got to feel the comfort of a death that was not ugly or painful or difficult. It was sad -- it's still sad -- that my grandma died three years ago. But what a privilege it was to be part of the day she left this world.

Susan DeWilde left this world in much the same way -- with loved ones by her side. She was a fighter and had conquered several rounds of breast cancer, a tumor in her spinal cord, uterine cancer, lymphatic cancer, and then leukemia, which took her life at the age of 53. I don't know this from Susan herself but from her friend, Christy Mack -- who helped her accept her death and guided her into her own final moments so that she could escape her pain and die peacefully. Christy writes about her beautiful friend and her empowering death in an article that appears in the August 2006 Oprah Magazine. Titled Friends to the End, Christy's story details how she soothed her friend, cradled her hand, and talked her through her last breaths. She helped her on her way during a time her friend feared most. Christy writes, "What she and I shared the night she died was a precious gift of friendship, emotionally profound and sacred in its perfection. It broke my heart. It strengthened my soul."

This I understand.

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