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Posts with tag tooth

Thought for the Day: Drug-dispensing teeth a real possibility

I never would have predicted it -- that a tooth could become a tool for dispensing medication. But the refinement of such a creation is actually in the works and before long, you may be asking not for a gold or decorative tooth but for one capable of doling out your drugs in the exact doses and at the right times.

Think about this:

Researchers from Europe and Israel are working right now on a tiny dispensing system called IntelliDrug. Their goal is to create parts small enough they can fit into a false tooth placed in the back of the mouth. The device will release a specific amount of medication at certain intervals so patients receive the proper dosage right on schedule.

This invention, crafted by an Israeli dentist, could pick up the slack for people who forget to take medicine and could save lives for those whose lives depend on scheduled drug therapy. It could also allow for better absorption of medication into the body.

The IntelliDrug device will deliver medicine directly into the bloodstream through the lining of the cheek around the mouth. Saliva, meanwhile, mixes with the drug and carries it throughout they body in a manner more efficient than just swallowing a pill every few hours.

While researchers hope to one day turn their device into a replacement tooth, the apparatus -- consisting of a stainless steel housing, a pump, custom valves, a microprocessor, batteries, and a reservoir for the drug pill -- currently comes in the form of a block the size of two teeth. It is strapped to the the side of teeth and hugs the inside of the cheek. The unit can be removed, and a technician can refill the drug reservoir, clean the unit, and change batteries when necessary.

Clinical trials on pigs are ongoing. Human testing is expected to begin by the end of the year.

Gum disease may increase risk of pancreatic cancer

As if gum disease is not a painful enough experience, a Harvard study shows the disease can more than double the risk of pancreatic cancer. Additionally, those with a history of gum disease and recent tooth loss have a 2.7-fold increase in risk.

Previous studies have linked gum disease and pancreatic cancer, but smoking -- which contributes to both diseases -- has never been taken into consideration.

Researchers in this study, who controlled for smoking, followed 51,529 men for 16 years and found those who reported gum disease were 64 percent more likely to have pancreatic cancer. Nonsmokers with gum disease were twice as likely to develop the disease.

It was also determined in the study, published in the January 17 issue of the Journal of the National Cancer Institute, that the more severe the gum disease, the higher the cancer risk.

While it is not clear why gum disease is linked to cancer risk, researchers believe perhaps long-term gum infections trigger body-wide inflammation -- and inflamed tissues send chemical signals that promote tumor growth.

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