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Posts with tag transfusions

NFL coach Bill Walsh dies of leukemia

Bill Walsh, builder of an NFL dynasty with his 49ers of the 1980s, died of leukemia Monday at his San Francisco Bay. Walsh, known as The Genius for his innovative, pass-oriented attack, was 75.

Walsh was 102-63-1 with the 49ers and won three Super Bowls and six divisional titles in just 10 years. He was named Coach of the Year in 1981 and 1984 and was inducted into the Pro Football Hall of Fame in 1993. He served twice as the 49ers' general manager and coached at Stanford after leaving the 49ers.

"His coaching accomplishments speak for themselves, but the essence of Bill Walsh was he was an extraordinary teacher," says NFL commissioner Roger Goodell. "If you gave him a blackboard and a piece of chalk, he would become a whirlwind of wisdom. He revolutionized the game with his offense and will always be remembered as one of the most influential people in NFL history."

Continue reading NFL coach Bill Walsh dies of leukemia

FDA warns against common anemia drugs

Doctors prescribing anemia drugs for patients with kidney disease and cancer were urged by the Food and Drug Administration (FDA) on Friday to carefully dispense of these drugs due to an increased risk of death and other serious problems, such as blood clots, strokes, and heart attacks in patients with chronic kidney failure and rapid tumor growth in patients with head and neck cancer who receive doses higher than recommended.

The potentially harmful drugs, sold under than brand names Procrit, Epogen, and Aranesp, are genetically engineered versions of a natural protein -- called erythropoietin -- that increases the number of red blood cells. The drugs, with combined 2006 U.S. sales of $10 billion, are commonly used for patients with certain forms of kidney disease and for those receiving chemotherapy for cancer.

The FDA is adding warnings to the drugs' labels that will strongly instruct doctors to use the lowest possible dose needed to help patients avoid blood transfusions.

The FDA will also take a close look at how the drugs are marketed, including claims the drugs can improve the quality of life.

A meeting of FDA officials to further discuss this issue, believed to stem from drug overuse by dialysis centers and oncologists who make more money by using more of the drugs. is scheduled for May 10. Recommendations could lead to additional revisions of the drugs' labels.

Aerosmith Steven Tyler: cancer rumor Hep C secret tv video interview

Late last March fans of rock legend and Aerosmith lead singer Steven Tyler became concerned over speculation that Tyler had been diagnosed with throat cancer. Even though the remaining Rockin' The Joint show dates were cancelled, everyone connected to Tyler assured the public the rumors were false. Steven Tyler did not have cancer. He was suffering from strained vocal cords and needed a rest.

At the time, bassist Tom Hamilton explained the cancelled shows by saying, "You know Steven. Anything worth doing, to him, is worth overdoing," in reference to the fact that the band had been touring more now than it did 10 years ago.

Unfortunately, several months later it was announced that Hamilton had been diagnosed with cancer.

While the rumors had quieted concerning Tyler's health, now and then something new would come to our attention that made us wonder if he was okay. A reader wrote in that he had seen Tyler at the oncology clinic at a hospital he was visiting. We kept that under our hat.

Last night, Tyler appeared on Access Hollywood and for the first time, publicly discussed his health. No, he was not diagnosed with throat cancer -- but he had faced a serious health crisis and decided to speak about it. Tyler said he had been fighting a secret battle with a silent killer -- Hep C. Diagnosed three years ago, he was told by his doctor, Deepak Chopra's brother, that it was time he sought treatment. Tyler agreed to undergo a year of chemotherapy with interferon. He stated it nearly killed him but managed to stay with it and complete treatment. Tyler had Hep C for many years, and was asymptomatic, which is typical.

During the interview, Tyler said, "Hepatitis C is the one that, of all the people in this room, at least three have it and don't know it." He would like to raise awareness about Hep C and mentioned he might appear on Oprah for that purpose. "It's one of those things people don't speak about it, but it is treatable."

Almost 4 million Americans, or 1.8 percent of the U.S. population, have been infected with hepatitis C virus (HCV); it is the most prevalent cause of chronic liver disease in the United States. 80 percent of those with Hep C have no symptoms. Chronic hepatitis C can cause cirrhosis, liver failure, and liver cancer.

If you missed the television Access Hollywood interview with Steven Tyler, the video segment of the program is available online here.

Hep C and liver cancer

Did you know almost 4 million Americans, or 1.8 percent of the U.S. population, have been infected with hepatitis C virus (HCV); it is the most prevalent cause of chronic liver disease in the United States; and a segment of those suffering from chronic HCV, or Hep C, will develop liver cancer. Until this morning, I did not know.

But when someone close to you is diagnosed with this disease, numbers do not matter. Even if there were only two people on the planet with this diagnosis and one of the two happens to be someone you love, then it suddenly seems to become the number one disease.

In my preliminary research, I have found that 80 percent of those with Hep C have no symptoms. If symptoms do occur, they are likely to be jaundice; fatigue; dark urine; abdominal pain; loss of appetite and nausea. Skin rashes, extreme itching, muscle wasting and weight loss can also be signs of Hep C. For decades, you can have Hep C and not know it is taking its toll on the liver.

According to the National Digestive Diseases Information Clearinghouse (NDDIC), a distinct and major characteristic of hepatitis C is its tendency to cause chronic liver disease. At least 75 percent of patients with acute hepatitis C ultimately develop chronic infection, and most of these patients have accompanying chronic liver disease. Chronic hepatitis C can cause cirrhosis, liver failure, and liver cancer.

Those at highest risk for Hep C are intravenous drug users; recipients of clotting factors made before 1987; hemodialysis patients; recipients of blood and/or solid organs before 1992; healthcare workers, and infants born to infected mothers.

The treatments are harsh and can come with severe side effects that cause some to discontinue treatment. New research indicates that smoking marijuana seems to offset some of the adverse side effects of treatment and help those fighting this disease remain on treatment. Hepatitis Central has published an explanation of how Hep C infection can lead to liver cancer with Duke Researchers Show How Hepatitis Infection Leads To Liver Cancer, that I found helpful in understanding the progression of the disease.

As I say, I have just started my research this morning. With a critical eye, I will continue researching until I have exhausted every avenue of information, both conventional and alternative, that I can find. If any of our readers can suggest any resources for Hep C and/ or liver cancer, please leave this information in the comment area.

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