Colorectal cancer screening prevents more deaths due to early detection than breast or prostate cancer screening. The University of Michigan Comprehensive Cancer Center recently published a report on the 12 myths about colon cancer and getting to know them could save your life and the lives of your family and friends. Colon cancer is the second leading cause of cancer death in the United States, and the number one cause of cancer death among non-smokers.

Symptoms of colon cancer can include severe abdominal pain, blood in the stool or rectal bleeding, unexplained loss of weight, or major changes in bowel habits (recurrent constipation or diarrhea). But, these symptoms often do not occur until the cancer is in its more advanced stages. An absence of symptoms does not mean an absence of cancer. In fact colon cancer is often referred to as a "silent killer" because of the lack of symptoms until it is in advanced stages. A colonoscopy is the only method that can actually help prevent you from developing colon cancer in the future because during the screening colonoscopy, if the doctor finds polyps, they can remove them from your colon as part of the procedure, preventing the polyps from ever having the chance to develop into cancer. If the polyps found in your colon happen to already be cancerous, they can often be removed during your colonoscopy and treatment can begin right away.

When colon cancer is caught early, it has a 95 percent survival rate. That's why screening is so important. Once colon cancer has spread to the liver, it's usually deadly, with only a 9 percent survival rate. Colonoscopy screening is recommended for men and women beginning at age 50, unless other risk factors exist such as family history, obesity, smoking, ulcerative colitis or Crohn's disease.

Katherine Schaefer was investigating methods for treating the inflammation seen in Crohn's disease and ulcerative colitis when something terrible happened -- she noticed her carefully cultured cells were dead. And then something wonderful happened -- she realized she had stumbled upon a potential new method of attacking cancerous tumors that have become resistant to existing drugs.

Schaefer and her colleagues at the University of Rochester Medical Center in New York were testing a compound called a PPAR-gamma modulator -- a compound never considered a cancer drug, or a drug of any kind really -- when Schaefer made a calculation error and used a lot more of the compound than she should have. And her cells died.

Upon further study, Schaefer found the compound killed just about every possible epithelial tumor cell. These cells line organs such as the colon and also the skin. The compound, that works like taxane drugs but without eventual tumor resistance, also killed colon tumors in mice without making them sick.

The research team, whose findings are published in the journal International Cancer Research, plans more safety tests in mice. And eventually, if their outcomes are promising, they plan to design something they can patent as a new drug -- because they would love to see this disastrous lab experiment one day lead to treatment for cancers of the colon, esophagus, liver, and skin.

On July 20 in Portland, Oregon, Pearl Jam held a benefit concert for the Northwest Chapter of the Crohn's and Colitis Foundation of America (CCFA) to raise awareness for a disease no one likes to discuss. Pearl Jam guitarist Mike McCready was diagnosed with Crohn's disease and ulcerative colitis twenty years ago and has gone public with what he personally felt for many years was an embarrassing disease.

McCready, a spokesperson for the NW Chapter of CCFA, said, "Having struggled with Crohn's disease for more than 20 years and experienced first hand difficulties in getting a diagnosis and treatment, I want to help others learn about the disease, how it is affecting them and how to find ways to cope."

UCB, a leading global biopharmaceutical company that recently launched Crohns and Me, an information and resource website for people with Crohn's disease, joined with CCFA, in sponsoring the Pearl Jam Portland benefit concert.