• Lymph node
  
• Digital mammogram
  
• Next MRI
  
• Heart
  
• Colonoscopy

According to Pei Zhong, "HIFU in the current form can only be used to treat the primary tumor."

"We now think that HIFU delivered in a different mode, with emphasis on using mechanical vibration to break apart the tumor cells, may have an even more significant impact in suppressing cancer metastasis by waking up the immune system."

Ovarian cancer is hard to detect and is usually found in the advanced stages. It is the most deadly of all gynecological cancers. Transvaginal sonography (TVS) screening has been associated with detecting ovarian cancer at earlier stages of the disease.

TVS is a procedure used to examine the vagina, uterus, fallopian tubes, ovaries, and bladder. An instrument is inserted into the vagina that causes sound waves to bounce off organs inside the pelvis. These sound waves create echoes that are sent to a computer, which creates a picture called a sonogram. The test is also known as a transvaginal ultrasound.

The researchers' findings appear in the May issue of Cancer. In the study, colleagues assessed the value of annual TVS screenings in over 25,000 women. Participants had to be at least 50 years of age with no cancer symptoms or at least 25 years of age with a family history of ovarian cancer.

• A new ultrasound technique lets radiologists distinguish between malignant and benign breast lesions. Using elasticity imaging, researchers accurately identified harmless and cancerous lesions in almost all of the 80 cases studied. If results can be reproduced in a large trial, this technique could significantly reduce the number of breast biopsies required.

• Scientists seeking new treatment for diseases can use an online tool developed by researchers at MIT and Harvard. The Connectivity Map matches diseases with compatible drugs, based on the genetic profiles of both. So far, about 160 drugs and compounds are cataloged, and a few new uses for existing drugs have already been suggested. Eventually, all FDA-approved drugs will be included.

• For those who sometimes forget to take their pills, a new device -- that can be preloaded with up to 100 doses of medication -- could one day be implanted in the body and programmed to administer drugs via wireless signals. This device, successful in tests using dogs, was designed to deliver medicines that are less effective when taken orally.

• I fear a breast cancer recurrence, the return of a tumor that rises to the surface of my skin and presents itself again underneath my fingertips -- or in my worst-case scenario is lost among dense breast tissue, undetected by self-exam, and caught too late by some combination of mammogram, ultrasound, and MRI.

• I fear more than anything another cancer -- something entirely different from breast cancer, something buried in my body and not as responsive as breast cancer to treatment. I am prepared for a second visit from breast cancer because I know how to proceed, know I will succumb to treatment that is familiar, know I will remove both breasts in the most radical of life-saving approaches. But cancer in my lungs, brain, bones, blood, ovaries is out of my realm. And these cancers -- among many others -- really scare me.
  

• I fear that my mom and my sister -- my first-degree female relatives -- will one day follow in my breast cancer footsteps. I once thought family history trickled down from above, from older family members. Now I know the disease can start with anyone. I am the anyone in my family. I am the reason my mom and sister are closely watched and monitored and tested. I am the one that put the fear of cancer into their hearts and minds -- and into mine.
  

• I fear having another baby. I fear the return of cancer during pregnancy, leaving me with difficult choices regarding my health and my baby's health. I fear cancer returning after a baby is born, leaving me with one more child and more treatment to manage. I fear another cancer would lead to a decreased chance of survival and another baby would leave my husband feeling stranded should I die too soon. And I fear having a baby girl who would inherit the very real chance of developing breast cancer at some time during her life.
  

• I fear not having another baby. I fear the regret I may feel one day, perhaps 50 years from now when I am healthy and cancer-free and without the child I longed for. I fear I am being overly cautious, too tentative, a bit selfish. A fellow cancer survivor once wrote me, "I learned that my family continues, even if I do not. I also learned that they are at least as tough as I am so will cope with the genes I pass to them and their own cancer battles if needed. Finally, I learned they look out for each other just as I looked out for them. No matter what your future, you will never regret giving another child a place in your family." I fear this man may be right.
  

• I fear dying at a young age. I fear leaving my children before they are grown. I fear leaving my husband a single parent, my mom someone who has lost a child, and my sister an only child. I have been told over and over again that my chances of survival are great, fantastic even. I have a 93 percent chance of not dying from breast cancer. This does seem great -- until I take into account that this percentage is good for only five years. My five years will expire when I am 39 years old. What happens then, I am not sure. The only thing I am sure about is that five years is not enough time. I want more, need more, demand more. Yet I fear my days may be numbered.
  

The ultrasound technique called elasticity imaging might be able to reduce the amount breast biopsies given to patients. It works almost like a regular ultrasound examination of the breast except it is much more sensitive. The technique gauges how much tissue moves when pushed to detect how soft or stiff the mass is in the breast.

The study that was done showed that all 17 of the imaging studies thought to be malignant were found to be malignant after a biopsy was done. It also identified 105 out of the 106 benign lumps in the breast. From this study it suggests that elasticity imaging is 100 percent sensitive and 99 percent specific.

This could turn out be another useful tool used along with mammography and breast MRI's to detect a cancerous lesion in the breast. I, however, will always want a lump biopsied since I know that is the only way to know 100 percent whether it is malignant or benign.

(Thanks to Patti Anastasi for the tip)

I think I was the only one who truly believed the lump in my breast was cancer. No one else -- my mom, my sister, my husband, my doctors -- believed I was a candidate for this disease. I was young, had no family history, had no known risk factors. It just wasn't likely, even after an ultrasound revealed something suspicious.

The surgeon who performed my biopsy was in the same camp. It was probably nothing.

November 2004

On November 23, I had a biopsy. A large needle was placed in my breast and a piece of the lump was pulled out. The doctor had a hard time getting a piece, however, because it moved around so much. He said this was a good sign -- the movement. He sent the tissue to pathology and told me to call his office the next afternoon for the results.